Remarks
Larotrectinib is an orally available, tropomyosin receptor kinase (Trk) inhibitor, with potential antineoplastic activity. Upon administration, larotrectinib binds to Trk, thereby preventing neurotrophin-Trk interaction and Trk activation, which results in both the induction of cellular apoptosis and the inhibition of cell growth in tumors that overexpress Trk. Trk, a receptor tyrosine kinase activated by neurotrophins, is mutated in a variety of cancer cell types and plays an important role in tumor cell growth and survival.
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Reduce Bore
ApplicationÂ
Trunnion mounted ball valves are suitable for use on various kinds of pipelines of Class 150~Class 2500, PN16~PN160, JIS10K~JIS20K to cut off or turn on the pipeline medium, of which the operation types include worm gear, manual, pneumatic or electric actuators, being in general of flange connection, and butt welding ends connection as well.Â
Construction and featuresÂ
Urgent grease injection deviceÂ
Double-block and bleed functionsÂ
Fire safe designÂ
Self-relief in the body cavityÂ
The Bi-sealing design structure,i.e. seat sealing in front of the ball and seat sealing behind the ballÂ
Blow-out proof stemÂ
Anti-static designÂ
Mounting pad providedÂ
Standards and specificationsÂ
Design & Manufacture:API 6D?API 608?ASME B16.34?ANSI/AWWA C507?MSS SP-72?BS 5351?BS 6364?BFCI 70-2?ISO 5211?NACE MR0175 .Â
Connection Ends:ASME B16.5?ASME B16.47?API 605?MSS SP-44?ISO 7005-1?JIS B2238?BS 12627?ASME B16.25?ASME B16.11?BS 12760 .Â
Face to Face Dimension:ASME B16.10,ISO 5752,BS 558,BS 12982Â
Testing & Inspection:API 598?API 6D?API 607?API 6FA?BS 6755?BS 12569?MSS SP-82?MSS SP-61Â
Normal Pressure or Rating:Class 150 ~ Class 2500?JIS 10K ~ 20K?PN 10 ~ PN 160Â
Normal Diameter or Bore:NPS4~NPS36?DN50~DN900Â
Applicable Temperature:-196?~540
Operation Type:Manual, worm gear, pneumatic, electric
• Seat Material: PTFE, Nylon, PEEK, PPL, Molon, Develon, Delrin, RPTFEÂ
• O-ring Seals: NBR, Viton A, Viton AED, EPDM, Viton BÂ
• Stem/Ball/Seat Ring: 304, A105+ENP, 17-4PH, 4140+ENP, 316, 304L, 316L, LF2+ENP, 13Cr/Hard Cr, F51Â
• End Connection - Flange Ends/Butt Welding Ends
 Main Outline Dimensions
Class900
For dimension of size above 36", please contact SHITONG
Â
API Forge Steel Trunnion Mounted Ball Valve of 900lb Rb
Model NO.: QF
Type: Fixed Ball Valve
Function: Blow-Down Valve
Temperature: Normal Temperature
Application: Industrial Usage
Operation: Lever or Gear
Trademark: stong
Specification: 2"-48"
Origin: Chian
HS Code: 8481804090
API 3pcs Side Entry Forge Steel Trunnion Mounted ball valve of 900LBDN
L
d
Handwheel
Worm Gear Driven
Penumatic
Eletric
kg
mm
in
RF
WE
RJ
M
M0
B
B0
B1
B2
A
A1
A3
A4
D
D1
D0
RF
WE
80
3x2
381
381
384
49
123
650
-
-
-
-
234
174
148
257
-
-
-
58
48
100
4x3
457
457
460
74
-
-
185
400
200
106
343
258
287
287
-
-
-
105
90
150
6x4
610
610
613
100
-
-
225
400
200
108
427
322
378
378
-
-
-
230
162
200
8x6
737
737
740
150
-
-
389
600
330
144
587
457
530
530
522
337
508
470
370
250
10X8
838
838
841
201
-
-
449
600
330
144
725
595
530
530
606
421
508
530
410
300
12X10
965
965
968
252
-
-
497
800
370
220
795
630
680
680
684
482
508
1200
1030
350
14X12
1029
1029
1038
303
-
-
550
800
370
220
837
728
1455
1455
822
549
508
1695
1440
400
16X12
1130
1130
1140
303
-
-
550
800
370
220
837
728
1455
1455
822
549
508
1790
1480
450
18X16
1219
1219
1232
373
-
-
687
800
515
279
1314
1154
1665
1665
991
687
305
2520
2100
500
20X16
1321
1321
1334
373
-
-
687
800
515
279
1314
1154
1665
1665
991
687
305
2970
2430
600
24X20
1549
1549
1568
471
-
-
780
800
515
279
1459
1294
1665
1665
1105
772
305
5580
4520
750
30X24
1880
1880
1902
570
-
-
995
800
515
279
1075
915
1960
1960
1445
995
305
8980
7907
900
36X30
2286
2286
2315
712
-
-
1157
800
570
368
-
-
-
-
1661
1211
305
15650
13910